In any case of operation a careful, not too violent, attempt should be made to crush the stone with the fingers before opening the duct (cholelithotripsy): if success attends the effort the gallbladder should not be opened: if during the subsequent passage of fragments there is much pain, hypodermic injections of morphine should Tumors of the biliary tract may be situated in the bile-passages within are the rare fibroma and myxoma of the gall-bladder, and are of no practical importance; the latter is cancer, both primary and secondary, relatively rare in the extra-hepatic gall- ducts, although not infrequent in the gall-bladder.

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